Defy Medical Review
The most established telehealth TRT clinic with deep expertise in complex protocols.
Price
$200–250/mo
Founded
2013
HQ
Tampa, FL
Type
Telehealth + In-Person
Ready to get started with Defy Medical?
Starting at $200–250/mo · Telehealth available
Overview
Defy Medical is one of the OG telehealth TRT clinics, operating since 2013 — before most competitors even existed. Based in Tampa, Florida, they offer both telehealth and in-person visits, giving them a hybrid flexibility that’s rare in this space. Where Defy truly shines is complex cases. They have deep experience with multi-hormone protocols, custom compounding, and patients who have complicated health histories. If you’ve been on gear, have thyroid issues, need HCG alongside TRT, or have other hormonal complexities, Defy’s medical team has likely seen it before. Their pay-per-service model means you’re not locked into a rigid subscription — you pay for what you need, which can be more or less expensive depending on your protocol complexity.
Medications Available
Lab work: Comprehensive panels via LabCorp, customizable based on your protocol
Pros & Cons
Pros
- +Operating since 2013 — longest track record in telehealth TRT
- +Steroid-friendly with deep PED knowledge
- +Both telehealth and in-person options (Tampa)
- +Custom compounding and wide medication range
- +Flexible pay-per-service pricing
- +Handles complex multi-hormone protocols
Cons
- −Pay-per-service can get expensive for complex cases
- −Interface and tech feel dated compared to newer clinics
- −Consultation wait times can be several weeks
- −In-person only available in Tampa
Who Is Defy Medical For?
Defy Medical is the go-to for men with complicated hormonal situations — former steroid users needing PCT support, men on multi-hormone protocols, or anyone who wants a clinic with over a decade of experience. If you’ve tried a basic TRT clinic and they couldn’t handle your case, Defy probably can.
Pricing Breakdown
Defy uses a pay-per-service model rather than a flat monthly fee. Initial consultation runs $250–350. Follow-up visits are $100–200. Lab work is ordered through LabCorp (costs vary). Medications are priced separately through their compounding pharmacy. Total monthly spend averages $200–250 depending on your protocol. Annual cost: $2,400–3,000.
Our Verdict
Defy Medical is the wise veteran of the online TRT world. Their depth of experience with complex cases is unmatched, and having both telehealth and in-person options adds flexibility. The tech feels a bit dated and wait times can be longer, but the quality of medical expertise makes up for it. Best choice for men who need more than just basic testosterone replacement.
Frequently Asked Questions
How long has Defy Medical been operating?
Since 2013, making them one of the longest-running telehealth TRT clinics.
Can I visit Defy Medical in person?
Yes, they have a physical clinic in Tampa, FL. Most patients use telehealth, but in-person visits are available.
Is Defy Medical steroid-friendly?
Yes. They have extensive experience working with men who have PED history and design protocols accordingly.
How does the pricing work?
Pay-per-service: you pay for consultations, labs, and medications separately rather than a flat monthly subscription.